Mohamed S. Imam
Pharmacy Department, Alnahda College, Riyadh, Kingdom of Saudi ArabiaPublications
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Review Article
Impact of agonists of glucagon-like peptide-1 receptor in individuals with type 2 diabetes: A meta-analysis
Author(s): Mohamed S. Imam*, Fahad Saeed Algahtani, Naif Ayidh Alshabab, Manar Mesfer Eid Alsaadi, Mastora Shajea Falaj Alotaibi, Azoof Abdullah Naqi Alotaibi, Abdulrahman Abdullah Zaben Alnefaie, Retaj Awad AlNafie, Raghad Khaled Alzahrani, Sultan Ali A. Alqahtani, Saeed Hussain Saeed Alzahrani, Nawaf Mohammed A. Alhossan, Latifa Fahad Abdalwahap Almohsin, Ahmed Khalid Almutairi and Randa M. Abdel-Sattar
Background and objectives: We have done a meta-analysis to assess influence of glucagon-like peptide-1 receptor agonists (GLP1RAs) in individuals with Type 2 Diabetes Mellitus (T2DM). Beyond clinical relevance, GLP1RAs act through metabolic pathways that may also be influenced by plant-derived bioactive compounds, suggesting possible phytotherapeutic implications. Materials and methods: A thorough literature search conducted till January 2025 identified 10 studies encompassing 1,639,510 patients with T2DM at study’s inception. Study reported correlations between effects of Impact of GLP1RAs in individuals with T2DM. We computed Odds Ratio (OR) with 95% Confidence Intervals (CIs) to evaluate impact of Impact of GLP1RAs in individuals with T2DM, employing dichotomous method with either a random or fixed-effect model. Re.. Read More»