Identification and assay of the flavonoids in medicinal plants with hepatoprotective action

Abstract

Maria A. Cojocaru-Toma

The article describes the identification and assay of the flavonoids in medicinal plants with hepatoprotective action, harvested as a culture at the Cultivation Center of the Medicinal Plants within State University of Medicine and Pharmacy „Nicolae TestemiÈ›anu” from the Republic of Moldova, using Pharmacopoeia methods. The flavonoids, found in the examined medicinal product, are responsible for hepatoprotective activity due to antioxidant activity, exhibited by neutralizing free radicals. The flavonoids were identified by using the Chinode method and thin layer chromatography, operating with 3 systems of solvents, and as biomarkers rutine, quercetine and luteolin ewere used. The results of the quantitative analysis point out that the content of the flavonoids determined by using spectrophotometric method is in the range of 0.620% to 1.204%, in studied vegetal products.